Gao Xue-shan, styled Han Zhi, was a native of Kuaiji (now Shaoxing City) during the Shunzhi and Kangxi periods of the Qing Dynasty. In his youth, he studied Confucianism and was skilled in traditional Chinese medicine. While reading, he noticed that there were many seemingly correct but actually erroneous points in the Shanglun Pian by Yu Chang. In order to clarify these ambiguities, he wrote the four-volume work "Cold-Damage Disease Shanglun Bian Si." The book provides detailed annotations and analyses, and although it still has some flaws, it holds significant reference value.