disease | Congenital Toxoplasmosis |
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bubble_chart Overview It is a disease caused by the protozoan Toxoplasma gondii in the brain. The protozoan can also infect the fetus through the placenta, leading to stillbirth, premature labor, and congenital toxoplasmosis.
bubble_chart Diagnosis
- Brain membrane, encephalitis symptoms, and corresponding focal brain damage signs.
- Often accompanied by fever and headache.
- Increased eosinophils in blood and cerebrospinal fluid, with detectable pathogens, positive complement fixation, enzyme-linked immunosorbent assay, and indirect agglutination tests.
- Brain CT scans may show multiple low-density areas.
- History of contact with feline animals.
- Should be differentiated from other brain membrane inflammations, encephalitis, and similar conditions.
bubble_chart Treatment Measures
﹝Treatment﹞
Sulfadiazine, 2g~4g per day for adults (calculated as 50mg~150mg/kg for children), taken orally in 4 divided doses, along with pyrimethamine, 50mg per day for adults (calculated as 1 mg/kg for children), reduced by half after 2 days, with a treatment course of 15~30 days; alternatively, spiramycin 0.2g can be taken 3 times a day, with a treatment course of 10 days.