Subcutaneous nodules of the skin can occur at any age, in both men and women, and show no seasonal variation. This condition primarily results from skin damage secondary to subcutaneous nodule bacilli invading the skin or other organs. The disease follows a chronic course and may persist for several years or even decades. Before the liberation, subcutaneous nodules of the skin were relatively common in China. After the liberation, the people's governments at all levels placed great emphasis on the prevention and treatment of subcutaneous nodule diseases, establishing widespread prevention and treatment institutions. Efforts such as tuberculosis screening, universal treatment, and BCG vaccination, along with improvements in people's living standards, have made this disease rare in China today.

bubble_chart Clinical Manifestations

1. Skin lesions: lupus nodules, verrucous proliferation patches, ulcers, and scar formation;
2. Common sites: face, buttocks, neck, chest, etc.;
3. Generally no subjective symptoms.

bubble_chart Diagnosis

1. Skin lesions: lupus nodules, verrucous proliferation patches, ulcers, and scar formation;
2. Subcutaneous nodule bacilli found in smear of secretions from skin lesions;
3. Chest X-ray shows subcutaneous node infections in the lungs and other organs;
4. Histopathology reveals subcutaneous node lesions.

bubble_chart Treatment Measures

Treatment Principles

1. Supportive therapy;
2. Anti-subcutaneous node medication;
3. Chinese medicine therapy;
4. Topical medication therapy;
5. Surgical excision;
6. Physical therapy.

1. For mild cases, isoniazid and streptomycin can be the main treatments;
1. For cases with extensive skin lesions and recurrent episodes, the combination of isoniazid + rifampin or ethambutol is more effective.

TCM can effectively treat dry eye syndrome, floaters, retinopathy, and various chronic eye diseases

bubble_chart Cure Criteria

1. Cure: Symptoms and signs disappear, and all skin lesions subside;
2. Improvement: Symptoms and signs improve, and skin ulcers heal;
3. No cure: Symptoms and signs do not improve, and skin lesions remain unchanged.