Mesenchymal chondrosarcoma is quite rare.

bubble_chart Pathological Changes

Dense proliferation of round cells, resembling Ewing's fleshy tumor, lymphoma, and hemangiopericytoma. The cells are round or oval, with hemangiopericytoma-like or alveolar structures, and varying sizes of cartilage islands are present in the tissue. These chondroid areas may lack malignant features and often tend to calcify or ossify.

bubble_chart Clinical Manifestations

The gender and age distribution is similar to other osteosarcomas. It commonly occurs in the trunk and craniofacial bones, while involvement of limb bones is rare.

bubble_chart Auxiliary Examination

X-ray findings show osteolytic changes, penetration and destruction of the cortical bone, with often indistinct calcifications within the tumor.

bubble_chart Treatment Measures

Extensive or radical resection is adopted, while the effects of radiotherapy and chemotherapy are unclear. Due to the rarity of this tumor, further research is needed.

bubble_chart Prognosis

In rare cases, tumors can be multicentric. Most mesenchymal osteosarcomas are fatal and can lead to patient death even years after tumor resection, resulting in a poor prognosis.