The method of using bitter and cold herbs to clear interior heat, for example, when a patient has severe interior heat leading to dysphoria, even mania, retching, red urine, delirium, restless sleep at night, or hematemesis, nosebleeds, rashes, a yellow or dry black tongue coating with thorns, and a deep, rapid pulse, Coptis Detoxification Decoction (Coptis Rhizome, Skullcap Root, Phellodendron Bark, Gardenia) is used.