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The "toxin" referred to here is caused by extreme heat and is called "heat toxin" or "fire toxin." Using medications that can clear pathogenic heat and resolve heat toxin to treat conditions such as interior heat excess in sexually transmitted diseases, boils, sores, abscesses, and rashes is known as the method of clearing heat and removing toxin. Commonly used herbs include Lonicera, Forsythia, Isatis Root, Tokyo Violet Herb, Dandelion, and Barbated Skullcup Herb.

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