"Initial benefit, but rebound worsening" is a common saying. "Initial benefit" refers to the initial stage of taking medication when the effects seem very good; "but rebound worsening" means that as one continues to take the medication, it becomes less effective and may even produce adverse effects. This phenomenon is common in Traditional Chinese Medicine (TCM).

For example, a patient originally had cold hands and feet, loose stools, and poor energy. The doctor diagnosed it as yang deficiency and prescribed yang tonic. Initially, the medication worked very well, and the patient's condition improved gradually. The hands and feet were no longer cold, the stools became formed, and the energy improved. The patient was very happy and bought a month's supply of medicine to continue taking. However, over time, symptoms such as dry mouth, dry and hard stools, dysphoria, and dryness-heat in the hands and feet appeared. Upon returning to the doctor, it was found that the patient's constitution had become yang-excessive, leading to "heatiness." This is a common example of "Initial benefit, but rebound worsening."
Therefore, "Initial benefit, but rebound worsening" means overcorrecting, which naturally leads to adverse effects. Hence, after taking medication for a period, it is necessary to return for a check-up to let the doctor assess whether the condition is still slightly off, has returned to balance, or has been overcorrected.